The plot revolves around young lovers Lyka Raymundo (played by Angel Locsin) and Noah Ortega (played by Piolo Pascual). Lyka is a young woman aspiring to be a fashion designer, working as a fashion assistant in the House of Elle. She lives with her aunt Clara and her step cousin Anton.
Noah is the adopted son of General Leon Cristobal, who took over guardianship of Noah after his real father, Emil Ortega, died in a tragic accident involving an unknown wolf. Noah is a second lieutenant of the Philippine Army, being actively recruited to join the Luna force, an elite team specializing in protecting humans from dangerous werewolves and vampires.