The anthology film R246 Story centres around the major Japanese highway Route 246. The film consists of six segments.

Arifureta Kisho: The number of UFO sightings around Route 246 is on the rise. Four young men are doing traffic surveys on Route 246. One of them is trying to find his lost lover. This is a sci-fi film with a unique outlook on the world.

CLUB246: Juri is a stranger to dance clubs and girls. He has a huge crush on Saki, a girl who loves dance clubs. Set in a club, Juri's wild fantasies and crush on Saki accelerate.

DEAD NOISE: Japanese hip hop has established a firm position in Japan. But what goes on inside the heads of the artists currently leading the hip-hop industry?

Jiroru: Densetsu no Yo-na-o-shi: The legendary self-appointed magistrate, Mori no Ishimatsu travels in time from Shimizu City, the final stop on Route 246, to modern Tokyo! He tries to restore peace in the modern world, a world that has dismissed the concepts of "humanity" and "justice."

Bento Fufu: For quite some time, everyday routines have become too ordinary for an unmarried couple living together. Life seems to be good for them, but it also seems too mundane. The woman packs a nice lunch for themselves everyday, and the two have made it a habit to eat it together.

224466: An alien, "246" is unable to return home to his planet, Rock 'n' Roll. An old man (Torakichi) and a young girl (Shidomi) try to help get home. The story is a sci-fi fantasy, taking place on Route 246, the national highway stretching from Tokyo to Shizuoka.