Sonny Chiba is Wolfguy, the only survivor of a clan of werewolves who relies on his feral, full-moon-activated superpowers to solve mysterious crimes. One night, a bizarre and bloody death in the Tokyo streets plunges him into a far-reaching conspiracy populated by crooked politicians, naked white women, a phantom tiger, and a shadowy organization (called the J-CIA) out to steal the secret of Wolfguy's powers and the blood right out of his veins.